A show spokesman said Wednesday that representatives of the Philadelphia Eagles quarterback called late Tuesday to cancel his appearance for personal reasons. The daytime talk show host's interview with Vick was set to air Thursday, Feb. 24.
The interview was supposed to cover Vick's time in prison, his work with the Humane Society and his return to the NFL.
"After careful consideration, I will need to postpone the taping of the Oprah Winfrey interview scheduled for February 22," Vick said in a statement. "I admire and respect Oprah and hope to be able to participate in an interview in the future."
Vick missed two seasons and served 18 months in federal prison for a dogfighting operation based on his property in Surry County, Va. He was reinstated to the NFL for the 2009 season and has been doing public service work, including with the Humane Society.
Vick won The Associated Press' 2010 NFL Comeback Player of the Year award after leading the Eagles to the playoffs in perhaps the best season of his career. In 12 games, Vick threw for 21 touchdowns, ran for nine scores and passed for 3,018 yards.
The Associated Press contributed to this report.