Mawae hurt his right elbow on Dec. 21 early in the fourth quarter of a 31-14 rout of Pittsburgh. He has not practiced since and declined to elaborate on the nature of the injury.
Mawae said in a radio interview Tuesday that he wouldn't play Saturday. He did not practice Wednesday but wore a brace over his injured right elbow and tried snapping the ball a few times. The 15-year veteran said he snapped with his left hand in games previously in his career.
"I've just had it on just to get used to it," he said of the brace. "Day to day, normal stuff I don't have any issues. The football-minded things I've got to figure out how to work through, and it's part of the process of rehabbing and getting stronger."
Mawae also sustained an injury at the end of last season that kept him out of the Titans' wild-card loss at San Diego.
If Mawae can't play, second-year lineman Leroy Harris would start.
The Titans set a franchise record by allowing only 12 sacks during the regular season, tied with Denver for best in the NFL.
"From a personal standpoint, it's frustrating because I was brought here to be a leader of this team and help us grow to where we're at," Mawae said. "I'm not lost on the fact I'm part of why we're now 13-3. ... I think we have something special here. That's the hard part."
Copyright 2009 by The Associated Press.