After bumbling around all night, the Jets somehow still had a chance to win when they took over at the Tennessee 25 with 47 seconds left following a 19-yard punt by Brett Kern. But Sanchez fumbled a low shotgun snap, running back Bilal Powell inadvertently kicked the ball away and the Titans recovered to seal it.
It was a fitting end to an ugly game that left Ryan cursing to himself as he walked off the field. Sanchez finished with five turnovers -- one on each of his team's final three possessions. He has 24 this season and 50 total in the past two seasons combined.
"It doesn't feel good hurting your team like that," Sanchez said. "It's not a winning formula. It never feels good."
"I've just got to prepare as the starter and see what happens," Sanchez said.
"I just regret not winning this game," Ryan said. "I think that's the big thing."
The Jets (6-8) needed to win their final three games and get help elsewhere to earn a playoff spot. Instead, the Titans sacked Sanchez three times and got a fourth on Tim Tebow. Jason McCourty and Michael Griffin each had two interceptions. The Jets are now out of the playoffs for a second straight season, after reaching consecutive AFC title games.
Johnson, with the names of the victims of Friday's shootings in Connecticut written on his cleats, ran a franchise-record 94 yards for a TD in the second quarter. Johnson said he followed a block by center Kyle DeVan, the Titans' latest player at the position after replacement Kevin Matthews sprained his right ankle.
"Kind of heartbroken, so just something to try to give back and show tribute to those families knowing how much they hurt and a situation where on Monday Night Football everybody around the world is watching," Johnson said, explaining why he wrote the victims' names on his cleats.
Locker's 13-yard quarterback keeper around left end put the Titans (5-9) ahead 14-10 with 20 seconds left in the third.
The Jets had plenty of time and opportunity in the fourth to take the lead, but Sanchez kept giving the ball away.
Griffin intercepted Sanchez with 7:09 left on a pass intended for Braylon Edwards. On the next drive, the Jets got help from a personal foul when Titans linebacker Will Witherspoon hit Sanchez in the head with his helmet on third-and-4. A couple of plays later, Sanchez threw into triple coverage for Jeff Cumberland, and Griffin picked off Sanchez again with 1:51 left at the Titans 2.
Even with the ugly night, the Jets' defense gave New York one final chance after forcing Tennessee to punt.
Kern had a 19-yarder under pressure, giving New York the ball at the Tennessee 25. But Sanchez mishandled a low snap from center Nick Mangold, and Brown recovered to finally clinch Tennessee's win.
Sanchez was 13 of 28 for 131 yards and a touchdown. He finished with his most interceptions in a game since 2009.
The Jets even turned to Tebow for a complete series in the second quarter. They picked up two first downs and reached their own 44, but the drive stalled from there after a sack, a delay-of-game penalty and an incompletion.
The Jets kept Tennessee from scoring a single point off all the turnovers. But the damage already was done.
Sanchez put the Jets ahead 10-7 with a 17-yard TD pass to Cumberland with 3:19 left in the third quarter.
It marked Johnson's sixth career touchdown run of at least 80 yards, giving him twice as many as anyone else in NFL history. Barry Sanders, Ahman Green, Hugh McElhenny and O.J. Simpson each had three touchdown runs of at least 80 yards.
Johnson was otherwise held in check, finishing with 122 yards on 21 carries for his 32nd career 100-yard game.
The Jets grabbed a 3-0 lead when Nick Folk's 22-yard field goal capped their first possession of the night. New York appeared to reach the end zone when Cumberland caught a 4-yard pass from Sanchez on third-and-goal, but the original ruling of a touchdown was overturned after replays showed the ball hit the ground.
Copyright 2012 by The Associated Press