Why to watch
You have to think Drew Brees comes out fired up after throwing three picks a week ago in a tough loss to the Buccaneers. The Saints want to improve their ability to get after the passer and force turnovers as well. And if 2011 form holds, the Colts should happily oblige.
Peyton Manning got his massive contract, but has been unable to play and isn't sure when he will be back. Brees is playing every week but isn't sure when his massive contract is coming.