"I've been patient for eight weeks and, hopefully, it's my time right now," Austin said. "I knew the day was going to come. It was just me being patient and me being true to myself and to keep working. I'm just glad that I had an opportunity."
Nobody has done more against Indy (6-3) this season -- or any time recently.
Austin returned four punts for 145 yards and scored on touchdown passes of 57 and 81 yards, his only two catches of the day. He also returned one kickoff for 27 yards while making the Colts look foolish all day.
"I went from saying, 'Get away, get away, get away,' to 'Go, go, go!' " Fisher said.
Austin later caught a short pass on a drag route over the middle, turned upfield and avoided two defenders with an inside cut for the 81-yard score. That made it 35-0 -- too big a deficit for even the masterful Andrew Luck to overcome.
The Colts just couldn't get a handle on the 5-foot-8, 176-pound receiver who finished with 310 total yards and three touchdowns.
"That was a lot of fun to watch. Tavon, he's lightning in a bottle when he gets the ball in his hands," quarterback Kellen Clemens said. "His performance tonight is certainly going to be one for the books."
Clemens went 9-of-16 passing for 247 yards with two scores and no interceptions, hooking up with Austin on the two longest completions of his eight-year NFL career. His previous longest was 56 yards in 2007 with the Jets.
Luck was sacked three times, and the Rams picked off four passes -- three of them from Luck -- to win for the first time since Sam Bradford went down with a season-ending knee injury Oct. 20.
"We just didn't do anything," coach Chuck Pagano said. "I take full responsibility for it as the football coach, we did not have this team ready to play."
Luck finished 29-of-47 passing for 353 yards with one touchdown, though most of that came after the Colts dug themselves into a 38-0 deficit. Indy ran 14 times for a measly 18 yards, 1.3 yards per carry. The defense couldn't get a handle on Austin or his teammates, resulting in Indy's worst loss at Lucas Oil Stadium -- and its worst home loss since San Diego hung a 31-0 shutout at the RCA Dome on Nov. 29, 1993.
The loudest cheers, and most tears, came during a halftime ceremony. Army Sgt. 1st Class Jeremy Inocencio surprised his family by stepping out of an SUV in one of the end zones at halftime. His wife, Christin, and children, Dominique and David, ran toward him to give him a hug, drawing both cheers and tears. Inocencio had been serving in Afghanistan.
"It is what it is, we got our butts kicked, we've got to move on," said Pagano, who will take the Colts to Tennessee on Thursday night.
NOTES: Mathis also broke the franchise record for multi-sack games in a season (six) and has a new single-season career-high, too. ... The Rams played without starting right guard Harvey Dahl (knee) and second tight end Lance Kendricks (broken finger) and lost linebacker James Laurinaitis late in the game with a head laceration. ... Indy had won two straight overall and five straight over NFC opponents before Sunday. ... Indy, which had only six turnovers all year, had four Sunday. ... It was the Rams' first regular-season trip to Lucas Oil Stadium.
Copyright 2013 by The Associated Press