The most serious injury appears to be Lichtensteiger, who told NFL.com's Steve Wyche he would be out for the season after tearing the anterior cruciate and medial collateral ligaments in his right knee. Shanahan also indicated Lichtensteiger suffered injuries to the ACL and MCL ligaments to reporters.
"(We're) not really sure right now," Shanahan said. "He's quite sore. It doesn't look good."
Shanahan also said it "didn't look good" for Williams, who limped off the field during the second quarter after his right leg was rolled up on from behind. Shanahan wouldn't speculate on how long Williams would be out and said he would know more later in the week. Williams left the stadium in a walking boot, according to Wyche.