Bradford hasn't done much work since Friday in hope that the extra rest would help heal his high left ankle sprain.
"It's been a shutdown deal," Spagnuolo said.
Defensive tackle Darell Scott, who also sustained a concussion, was sent home by the team Monday. Spagnuolo added that a CT scan on Scott also came back negative.
Justin King has a groin injury, and Spagnuolo didn't believe the cornerback would be available for the next practice Wednesday, further depleting a thin position.
Copyright 2011 by The Associated Press