Huff was limited in Friday's workout and is listed as questionable on Oakland's injury report -- one of several players whose status remained in doubt when the team left for its cross-country flight Friday.
Unlike starting wide receiver Jacoby Ford, who has already been ruled out with a hamstring injury, Huff is planning to play.
"I'll be all right," Huff said following practice. "Haven't missed a game in my career. Why start now?"
Oakland couldn't afford to be without Huff for long. Backup strong safety Mike Mitchell has been sidelined since early in training camp because of an upper leg injury. Jerome Boyd hadn't even played a regular season game in the league until last Monday night in Colorado.
Coach Hue Jackson is optimistic that Huff -- who signed a $32 million, four-year deal in August to return to Oakland -- can play in Buffalo but declined to say who would start if he can't.
"It will depend on how we start in the backfield," Jackson said. "We have some bodies back there if he can't go. But I feel very comfortable that we'll have all these issues solved and be ready to play this game."
Giordano would likely be tabbed if Huff is unable to play.
It's a good thing Jackson decided to keep seven receivers on his roster.
Copyright 2011 by The Associated Press