It was over when ...
The Patriots scored touchdowns on two consecutive second-quarter drives. The first was an 8-yard pass from Tom Brady to TE Benjamin Watson. That was followed by a 3-yard pass from Brady to Randy Moss. The second score gave the Patriots a 17-7 halftime lead.
Brady went 23-of-29 for 311 yards, throwing four touchdowns -- two to Moss (115 receiving yards), and one apiece to Watson and Jabar Gaffney.
Bills QB J.P. Losman was injured on the first play of the game, when Patriots DT Vince Wilfork rolled into his left knee. Losman stayed in but fumbled the ball two plays later. He was replaced by rookie Trent Edwards, who finished the game 10-of-20 for 97 yards and one interception. ... Bills Rookie LB Paul Posluszny left the game in the second quarter with a broken left forearm. ... The Patriots totaled 38 points for the third consecutive time this season. ... Moss and Watson have scored touchdowns in all three of New England's games this season. Moss has scored a touchdown in each of his four career games vs. Buffalo. ... The Patriots used both of their challenges in the span of three plays in the second quarter, and both were unsuccessful. ... Leading 38-7 in the fourth quarter, the Patriots inserted backup QB Matt Cassell.