The Steelers have won 14 of the last 16 meetings, including the postseason, and lead the overall series, 18-5.
Keep your eye on ...
Indy's front line: Finally completely healthy, the Colts' offensive line has not allowed a sack on Peyton Manning in its last three games. It will be challenged to continue that trend against Pittsburgh, which has a league-leading 32 sacks, including seven against Washington on Monday night.
Parker's participation: Willie Parker returned last week after a knee injury kept him out of Pittsburgh's previous four games, but now a shoulder injury has put Parker in jeopardy of missing Sunday's game with Indianapolis. If Parker can't go, the Steelers will be confident in the ability of backup Mewelde Moore, who has 314 rushing yards, and four touchdowns in four games as Pittsburgh's starter.