This is the way the Harbaugh era ends, not with a bang but a record-setting whimper.
The 355 rushing yards is the most by any team in a loss since at least 1950 -- consider it the cherry on top of the 49ers' crap sundae season.
Jim Harbaugh's team squandered a 21-point third-quarter lead and wasted their best offensive performance of the season. Their 447 total yards snapped an eight-game streak of fewer than 350 total yards and a three-game streak under the 250 mark. The Niners had scored fewer than 20 points in seven of the past eight games.
The 21-point letdown is tied for the third largest in team history and marked the first four-game losing streak of the Harbaugh era.
Still it wasn't enough to give Niners fans one last glimpse of hope before the sun sets on this forgettable season.
"Yeah, it sucks," left tackle Joe Staley said. "Yeah, I mean ... yeah, frustrating season, frustrating game."