LANDOVER, Md. (AP) -Rex Grossman completed 21 of 34 passes for 305 yards and two touchdowns for Washington.
Making his first Week 1 start since 2007, Grossman justified - at least for a week - coach Mike Shanahan's decision to go with the veteran over John Beck after a quarterback competition that lasted the entire preseason.
This one was ugly with mistakes by the Rams giving New York a much-needed win after a disappointing loss to Washington in the season opener.
Vick started despite suffering a concussion in last week's 35-31 loss at Atlanta. He left with a broken right hand in the fourth quarter after helping the Eagles overcome a 14-0 first-quarter deficit to take a 16-14 lead.
GLENDALE, Ariz. (AP) - Eli Manning threw two touchdown passes in a 58-second span late in the game to rally New York.
Manning completed 7 of 8 for 126 yards on the decisive drives as the Giants won their third in a row. He finished 27 of 40 for 371 yards. Nicks caught 10 for 162 yards.
Wells rushed for a career-best 138 yards.
A procedure penalty on first down pushed the ball back to the 10, then Eli Manning's pass tipped off Cruz's hands, bounced off Kam Chancelor and was picked off at the 6 by Browner.
EAST RUTHERFORD, N.J. (AP) - Ahmad Bradshaw ran for 104 yards and a career-best three touchdowns and Lawrence Tynes kicked a go-ahead 23-yard field goal with 1:32 remaining for New York.
Fitzpatrick also was intercepted twice by Corey Webster, with the last starting the possession that led to the winning kick.
Manning completed a pair of long fourth-down passes and got the Giants down to the 10, but on fourth-and-2 with 1:51 left, Smith made a leaping right-handed smack of the ball.
On third-and-goal, Young found Cooper, who hadn't caught a pass all season, alone in the end zone for the lead that gave the Eagles hope in what has been a dismal season.
This was a game New York was desperate to win after losing its previous two to San Francisco and Philadelphia.
New York tied the game on Eli Manning's 2-yard touchdown pass and a 2-point conversion run by D.J. Ware with just under a minute to play.
Cruz, who had three catches for 164 yards, broke Amani Toomer's single-season mark for yards receiving - and the team's record for longest touchdown reception, a 99-yarder that gave the Giants the lead for good in the second quarter.
New York won three of its final four games and earned a wild-card home game against the Atlanta Falcons.
He also threw a 4-yard TD pass to Nicks in the first half, which came after the quarterback scrambled 14 yards to spark the 85-yard drive.
While Manning came through with touchdown passes, the tempo was set by New York's defense, which never allowed Atlanta to get going, and the league's lowest-ranked rushing game, which ran for a season-high 172 yards. Brandon Jacobs led the way with 92 yards on 14 carries.
GREEN BAY, Wis. (AP) - Eli Manning threw three touchdown passes and the New York Giants shocked Green Bay 37-20. The Packers (15-2) might have been the reigning Super Bowl champs, but the Giants have been on a roll ever since beating the rival Jets on Dec. 24, beating the Dallas Cowboys to get in the playoffs and then blowing out Atlanta in the wild card round last week.
Manning, who threw for 330 yards, did the most damage with his throws to Hakeem Nicks, who caught seven passes for 165 yards and two touchdowns.
Aaron Rodgers was 26 of 46 for 264 yards, with two touchdowns and an interception. He also was the Packers' leading rusher with 66 yards on seven carries. But Green Bay had a handful of drops and lost three fumbles, including one on a rare giveaway by Rodgers. The Giants also sacked Rodgers four times.