Polian said Manning has been receiving "conservative" treatment for the inflamed bursa sac since February. He said that treatment was effective until Manning experienced increased pain and early signs of infection.
Manning has started 160 straight games dating back to the first game of his rookie season. He has the longest streak in the league if Brett Favre remains retired.
"I'm going into my 11th year. I'm 32, but I really feel I'm in a younger body than that," Manning said last week. "I feel I'm in a 28-year-old body because I've had great protection from my offensive line. I feel that's hopefully going to allow me to play a number of more years."