The NFL celebrates its 100th anniversary in 2019.
To commemorate the notable benchmark, the NFL has 17 matchups with historical significance in mind.
The 2019 regular season kickoff features the NFL's oldest rivalry, which began in 1921. The Packers hold the all-time edge in the series with a 96-94-6 record.
The two teams squared off in the 1981 AFC Divisional Round and produced one of the most thrilling games in league history. Led by current CBS Sports analyst Dan Fouts, the Chargers pulled off a 41-38 win in overtime. Fouts completed 33 of 53 passes for 433 yards and three touchdowns with an interception in the win.
Buffalo and Tennessee captivated audiences with the Music City Miracle in the 1999 playoffs. With 16 seconds remaining in the game and the Titans facing a 16-15 deficit, fullback Lorenzo Neal fielded a short kickoff, made a move to his right, and then handed the ball off to tight end Frank Wychek. The tight end took a few steps to his right before stopping, and then turned his body to the left and threw a lateral across the field to an uncovered wide receiver Kevin Dyson, who raced 75 yards down the left sideline untouched for the game-winning touchdown.
The two teams are bitter rivals, but the Saints' win on Sept. 25, 2006, brought out a lot of emotions with the reopening of the Superdome following the city-wide devastation from Hurricane Katrina in 2005.
Perhaps a sign of the times, but what happened on Nov. 17, 1968, when the game was cut off on the East Coast to show the film "Heidi" isn't likely to ever happen again.
These two teams met in Super Bowl XLVII, and the matchup at the Superdome featured brother versus brother (Jim and John Harbaugh) on opposing sidelines along with an infamous power blackout.
The Raiders and Chargers produced the "Holy Roller" game in 1978 and the result forever changed the NFL's rule on an offense's ability to advance recovered fumbles. In the contest, Raiders quarterback Ken Stabler avoided a sack by throwing the football forward towards the goal line. Running back Pete Banasnak touched the ball, then used both hands to shove the football forward. Tight end Dave Casper then recovered the football in the end zone to give the Raiders a 21-20 win.
Week 17: TBD