According to NFL Media's research department, Gray currently stands as the first player since at least 1940 to rush for as many touchdowns as the rest of the NFL combined in a given week.
The four-touchdown outing was the first by a player without a previous NFL touchdown since 1921.
The former Notre Dame star's manifold accolades beg a follow-up question: Is this a sign of things to come or a one-game aberration?
As NFL Media analyst Brian Baldinger points out on NFL NOW, Gray was at the eye of a perfect storm Sunday, offering a power-back skill set ideally suited for the game plan specific to an Indianapolis defense that rolled over for 234 rushing yards and six touchdowns at New England last January.
Patriots owner Robert Kraft even pulled Gray aside last week to tell him he would have a "big game" as the offensive focal point, per NFL Media's Judy Battista.
No coaching staff is better at tailoring game plans and personnel groupings to each opponent, while fully exploiting the niche skill sets of late-round draft picks and street free agents.
"We've got a lot of weapons," Gray said, via Battista. "You never know when guys will have a big game."