Harbaugh said the 49ers were still waiting for final results from team doctors but it "looks like we'll be all right." Smith walked out of the locker room without talking to reporters.
The 49ers drafted Smith seventh overall last year. He racked up a franchise-rookie record 14 sacks -- best among NFL rookies -- to go with two forced fumbles. Smith was the runner-up to Denver's Von Miller for the AP NFL Defensive Rookie of the Year award.
The Associated Press contributed to this story.