Brissett went down early in the second quarter after a short incompletion on first-and-goal from the 12-yard-line. The Colts QB jogged to the sideline and was checked by trainers on the sideline.
Guard Quenton Nelson was pushed back into the quarterback and stepped right on Brissett's left leg. The QB went down in obvious pain but was able to make his way to the sideline without assistance before ultimately going into the blue medical tent. Brissett never returned to the game.
"I think it looks like a sprain, but we'll see to what degree," Reich said, per 1070 The Fan. "We have to see how it responds."