Jacobs is dealing with a fractured shoulder blade and has played through it the past five weeks since sustaining the injury in Green Bay. The rookie RB was considered a game-time decision for the matchup after being listed as questionable on the injury report and missing two practices this week.
Rapoport added that Jacobs will have an MRI this week on the injured shoulder.
Entering Sunday, the rookie is fifth overall in rushing with 1,061 yards and seven touchdowns, and is on the brink of Raiders history. Jacobs is the first Raiders running back to eclipse 1,000 yards since Latavius Murray did it in 2015, and he's a top candidate for offensive Rookie of the Year, which hasn't been won by a Raider in nearly 40 years since Marcus Allen was awarded the honor in 1982.
Here is other injury news we're monitoring on Week 14 Sunday:
As for the Texans secondary, cornerbacks Bradley Roby (hamstring) and Gareon Conley are each active.
»Baltimore Ravens wide receiver Marquise Brown (ankle) and cornerback Marlon Humphrey (thigh) are each active to play in Buffalo. Both practiced fully on Friday.
»Minnesota Vikings wide receiver Adam Thielen (hamstring) is officially inactive for Sunday as he recovers to get the scar tissue out of his leg, but all parties are optimistic he will be on the field next week, according to Rapoport. No extended absence is expected.
» New Orleans Saitns linebackersKiko Alonso and A.J. Klein are each inactive in the team's big showdown with the 49ers. Standout offensive lineman Terron Armstead is active, however.