With most of its starters on the bench, Indianapolis earned a franchise record for wins in a season (14) with a 17-13 victory over Arizona in Week 17 of the 2006 season.
Keep your eye on ...
Warner's early results: The Pro Bowl quarterback was at his best in last week's win over the Jaguars. He began the game on fire and set the regular-season record for completion percentage (min. 20 attempts), connecting on 26 of 28 passes. He could have a tougher time establishing a rhythm this week against the Colts' top-ranked pass defense.
Peyton Manning's efficiency: Despite having the ball for less than 15 minutes against the Dolphins, Manning was still able to throw two touchdown passes and help the Colts put up 27 points. While Arizona does not run the ball-control-type offense that Miami does, the Cardinals are explosive and Manning may have to post big numbers again for Indianapolis to win.
The Colts' energy level: Though it won Monday night, Indianapolis still endured a physical battle against Miami -- especially defensively. The Cardinals, meanwhile, were able to generally coast against Jacksonville after taking a big early lead. Will the Colts have enough in the tank on defense to deal with the rested and high-powered Arizona offense?
Did you know?
The Colts have the league's longest active regular-season winning streak at 11. ... Since 2007, Dallas Clark leads all NFL tight ends with 18 touchdowns. ... Arizona's Tim Hightower has the most receptions of any running back in the league with 15.