**Has Rex lost his edge?: ** Since 2010 (his last playoff appearance), Rex Ryan has posted a .436 win percentage and zero winning seasons.
**Running at will: ** The Bills have a league-high four games of 200+ rushing yards this season.
**Mind-blowing stat: **LeSean McCoy has four games of 100+ rush yards and 2+ TDs this season (most by a player in a season since Chris Johnson in 2009).
**Down year for Tyrod: **Tyrod Taylor's passer rating has dropped 12.6 points below his passer rating from last season (99.4).
**Not suited for shootouts: ** The Bills are 7-1 when allowing 21 or fewer points this season. They are 0-6 when allowing 27+ points.