Eli won't be the first Manning to host the show. His brother, Peyton, did it in 2007 and had a very funny "United Way" skit in which he coached youngsters, hit them with passes in the back and stomach and even banished one to a portable bathroom for 20 minutes.
Eli Manning has no stage experience, noting he was never even in a school play, though he's done several commercials.
"It's something that's been offered a few times and I've turned it down. But it seemed like the right time. I felt ready to do it and I'm excited about that opportunity," he said Monday.
"I'm a little nervous about it, but excited also. It should be a lot of fun. It will take some work, but it should be something I'll always remember."
Asked if he'd make a guest appearance to help his little brother out, Peyton Manning said he has a prior commitment, "so I won't be able to make it. But I'll be tuned in."