"Drew Brees will be out for this game," Payton said. "He'll travel, and I think just where he's at in the rehab and his strength, that he felt, and we all felt like it would be too early for him to play this weekend.
"I would say next week we'll continue the process, and without trying to make an estimation about his return, we felt like he made progress throughout the week, and yet he's not where he needs to be or where we feel comfortable with the strength that he needs. But he did get better each day and we'll just see where he's at next week."
NFL Media Insider Ian Rapoport first reported that Brees suffered a rotator cuff injury that could keep him out multiple weeks. Brees has remained optimistic, telling reporters he was "pretty confident" he'd be on the field against the Panthers. Payton said "the velocity wasn't there" when Brees threw this week.