Brees returned to practice on a limited basis on Friday and was officially listed as questionable.
The veteran quarterback has insisted all week he'd play despite the painful injury to his right foot, adding that the game plan wouldn't be restricted with him on the field.
"It hurts to walk. It has its challenges," Brees said earlier this week, via ESPN.com. "But we've come up with a good plan for this week, how to support it and how to make it as manageable as possible."