The Steelers sat Ben Roethlisberger, running backs Le'Veon Bell and DeAngelo Williams, wide receivers Antonio Brown and Markus Wheaton, and center Maurkice Pouncey. First-round pick cornerback Artie Burns missed the game with a nagging thigh injury, while linebackers Bud Dupree and Jarvis Jones - former first-round picks - also sat out.
Jones finished 6 of 12 for 55 yards and a score.
Andre Roberts scored on a 28-yard pass from Orlovsky before the two-minute warning. Orlovsky finished 16 of 25 for 164 yards with a touchdown and an interception.
Copyright 2016 by The Associated Press