The Colts placed veteran backup Kerry Collins on injured reserve Tuesday with a concussion, officially ending his 17th NFL season.
Luring Collins out of a one-month retirement in August to bridge the gap until Manning returned from neck surgery didn't pan out for the 0-7 Colts or the quarterback. Collins started the first three games of the season with mediocre results and suffered a concussion in Week 3 against the Pittsburgh Steelers, forcing the Colts' transition to Painter.
Indianapolis still has three quarterbacks on its active roster -- Painter, Manning and recently re-signed Dan Orlovsky.
Collins completed 48 of 98 passes for 481 yards and two touchdowns with one interception this season. But it could be the end of the road for Collins, who has appeared in 198 career games and thrown for 40,922 yards (10th most in NFL history) and 208 touchdowns with 196 interceptions. He had been limited to light individual work at practice since suffering the concussion.
The Associated Press contributed to this report.