Jackson was sidelined during the third quarter against Carolina with what was initially reported as a neck injury and did not return. The injury was later diagnosed as a concussion. Jackson met with doctors on Monday and felt sufficiently recovered to where the Colts now fully expect that he will play against the Patriots.
Jackson, the team's second-leading tackler this season, was injured early in the third quarter while breaking up a pass intended for Carolina tight end Jeff King.
Jackson, who entered the game with 35 solo tackles, recorded one tackle before leaving with the injury.
The Associated Press contributed to this report.