Coach Jim Caldwell said Wayne hurt the soft tissue below his kneecap. Wayne is listed as probable and Caldwell plans on him playing against New Orleans. Wayne got through the injury most of the season.
Caldwell said Freeney might do some running or participate in a simulated practice later in the day. Freeney hopes to work out Saturday.
Earlier Friday, Caldwell said Freeney's recovery was "trending in the right direction," a message he reiterated after the workout at the Miami Dolphins' team complex.
"This is right in line with our plans," Caldwell said. "He's making very good progress."
Left guard Ryan Lilja returned to practice after missing Thursday's workout with a sore back. He is listed as probable.
Indy has one more workout scheduled, a 40-minute walkthrough Saturday at noon, and Caldwell liked what he saw.
"These practices were right in line with what we've done all year, and we're pleased," he said. "Things have worked out great for us here."
The Associated Press contributed to this report