Gordon has missed the past two games after suffering a knee injury. Ekeler was hurt in Sunday's victory over the Bengals on an onside kick at the end of the game. Gordon, for his part, believes there's still a chance he could play.
"I definitely feel it will be a game-day decision," Gordon said, per Gilbert Manzano of the Orange County Register. "Still trying to decide what we're going to do. I know coach is trying to be careful, doesn't want me to further hurt myself."
Ekeler, who is in concussion protocol, did not practice on Tuesday, while Gordon was limited.
Jackson would get the start and figures to see the bulk of the backfield touches. A seventh-round pick out of Northwestern, Jackson displays burst through the hole and power on the second level, compiling 75 rushing yards on 15 rushing attempts with one touchdown the past two games.