Wells has been limited in practice all week after an allergic reaction to Orthovisc that was injected as a lubricant intended to ease discomfort in his right knee.
After Wells practiced more Friday than he had all week, Cardinals coach Ken Whisenhunt said that as long as there are no swelling problems Saturday, the running back should be able to play Sunday.
The knee swelled up immediately after the injection and had limited Wells in practice Wednesday and Thursday. The second-year pro from Ohio State missed the first two games of the season after injuring the knee in the final preseason game, requiring arthroscopic surgery.
For the rest of the Cardinals, linebacker Clark Haggans (groin) is listed as doubtful, while defensive tackle Alan Branch (back), wide receiver Steve Breaston (knee), linebacker Will Davis (groin), wide receiver Early Doucet (groin) and defensive end Kenny Iwebema (shoulder) are all listed as probable.
The Associated Press contributed to this report.