Sunday's win-and-in bout between the Arizona Cardinals and Los Angeles Rams won't feature two backup quarterbacks.
"There's no holding back ... my leg. ... I'll be fine," Murray said, via NFL Network's Omar Ruiz.
Murray went down on Arizona's final play of Week 16's 20-12 loss to the San Francisco 49ers with a leg injury.
The second-year QB was able to practice Wednesday, paving the way for him to play in Sunday's pivotal tilt.
Murray has averaged 313.3 offensive yards per game (combined pass and rush YPG) and has 37 TDs (26 pass TDs, 11 rush TDs) this season. He's one of three QBs since 1950 with 35-plus offensive TDs and 300-plus offensive YPG in their second NFL season (others: Dan Marino and Patrick Mahomes).
Murray playing will keep Chris Streveler as the backup.
If the Cardinals win Sunday's bout, they are in the playoffs. The Rams can make the postseason with a win or a loss, if the Chicago Bears fall to the Green Bay Packers.