C.J. Anderson is expected to miss at least a few weeks with a bone bruise in his right knee, NFL Network's Mike Garafolo reported, via sources informed of the injury.
Anderson is seeking a second medical opinion on the knee. Depending on the results, it's possible that he could miss the remainder of the season, NFL Network Insider Ian Rapoport added, per a source with knowledge of the situation.
Although Anderson suffered the injury late in the first quarter of Monday night's game, he returned in fine fashion with 84 more yards on 14 carries the rest of the way.
The multi-week absence is poor timing for Anderson, who is coming off of his best rushing performance of the season.
While the coaching staff has made it a point to get Devontae Booker more involved in the offense, the plan was for the rookie to work in tandem with the veteran, keeping a fresh back in the game at all times. Booker's 4.8 yards per carry leads the team, but he can't replicate Anderson's prowess in pass protection or route running.