Manning's streak of 51 games with a touchdown throw -- three shy of Drew Brees' NFL record -- ended on a sun-splashed, almost still afternoon with the game-time temperature a balmy 63 degrees. Despite three turnovers, the Broncos (10-3) won their third straight game since changing from a pass-oriented attack to a run-heavy approach.
"I hope fans will still keep coming to the games," Manning deadpanned.
The five-time MVP who's made a living throwing the ball insisted he's fine with handing it off.
"I'm comfortable with winning," Manning said. "That's what I'm comfortable with."
And he said he's enjoying watching Anderson, who contributed a tough 58 yards on 21 carries, as much as the fans are.
"Sometimes I get a minus on my grade sheet for not carrying out my fake, but I like to kind of watch him," Manning said. "He makes a lot of guys miss."
"Today was tough and a struggle, but at the end the day we got the 'W,' and he's proud about that, and we're proud about that," Anderson said.
Any week, he said, Manning "can go out there and throw eight touchdowns. We all sat here and saw him throw seven touchdowns (against Baltimore last year). I don't think there's anything wrong with 18, I think he's completely fine. It's up to us to help him."
"This was not the game for the receivers to have a lot of big numbers," Manning said, "but Wes' play helped us get this victory."
His 38 completions tied a team record, and his 57 attempts is a franchise high.
"Not good enough to beat a good football team," said Orton, who was sacked four times.
"They've got a great defense," Buffalo receiver Sammy Watkins said. "They do a lot of things, a lot of moving parts moving around, a lot of switching off, so you have to be disciplined."
A month ago, Denver's offense was a mess, with the line taking heavy heat after Manning threw 54 passes and handed off just nine times in a decisive loss at St. Louis.
"As you guys know, three weeks ago we weren't nothing, we were garbage, we were terrible," Orlando Franklin said, repeating some of the things that were said about his O-line last month.
After holding Buffalo without a sack for the first time in more than a year, Denver's line is being praised, not pilloried.
"You have to give it to the big boys up front," said Anderson.
Copyright 2014 by The Associated Press