The move signals the likely end for Harvin in Buffalo and perhaps could be the final stop in the 27 year old's career.
Two weeks ago one source told Around The NFL's Conor Orr retirement was certainly an option after he missed the team's game in London. Bills coach Rex Ryan insisted earlier this week that he believes Harvin wants to continue to play.
"He's in the building, I think," Ryan said during Monday's news conference. "He's obviously in the training room a little today. We'll see how it goes, but I know he wants to play and wants to contribute to this team."
Harvin has 19 catches for 218 yards and one score on the season.
Placing him on IR gives Harvin a chance to heal -- again -- and contemplate his future in the NFL. He's set to be a free agent in 2016 after signing in Buffalo this offseason.