**Marcell Dareus' impact: ** With DT Marcell Dareus on the field, Buffalo allowed 17.0 points per game this season. Without Dareus, Buffalo has allowed 33.0 PPG and 13 rush TDs.
**Defensive drop-off: ** In their last three games (all losses), the Bills have allowed 45.0 points per game and 414.0 yards per game.
**Lacking a pass rush: ** The Bills' defense has produced just 15 sacks so far this season (T-29th in NFL).
**Bright spot: **The Buffalo offense has scored a TD on 61.5 percent of red-zone trips this season (6th-best red-zone TD percentage in NFL).