A statement released by Davis reads as follows:
"After a few years of thought, I've decided it will be best for me to take a year or so away from the NFL. This will be a time for me to allow my Brain and Body a chance to heal. I know many won't understand my decision, that's ok.
"I hope you too have the courage to live your life how you planned it when day dreaming to yourself growing up. Your Life is Your dream and you have the power to control that dream. I'm simply doing what's best for my body as well as my mental health at this time in my life."
Although the wording suggests a sabbatical, a statement released by the 49ers reads that Davis has "informed the team he plans to retire" from the NFL. Davis missed four games last season following a concussion.
NFL Media Insider Ian Rapoport reports Davis will pay back $4.66 million in salary bonus money due to his decision to retire, according to a source informed of his plans.
"We've got several options," coach Jim Tomsula said about replacing Davis at right tackle. "We drafted a guy and we have three guys that have experience playing the right tackle position that we feel really good about.
"Alex (Boone) has always been a possibility at either tackle. (Erik) Pears has obviously played more tackle, right tackle, in this league than he's played guard so we feel really good there."
The depleted unit up-front is far from the only concern in San Francisco.
The defections don't end there.
Tomsula might have expected to lead a rebuilding effort, but he couldn't have realized the extent of the excavation back in January.