Here are notable players listed in the Week 4 injury report.
Dolphins WR Jaylen Waddle (concussion) questionable for Sunday's game vs. Broncos
Dolphins wide receiver Jaylen Waddle, who was a limited participant in Friday's practice, is considered questionable to play against the Broncos as he remains in concussion protocol.
Chargers RB Austin Ekeler (ankle) to miss second straight game
Chargers running back Austin Ekeler will be sidelined for a second straight game due to an ankle injury as he was ruled out on Friday for Sunday's Week 3 game against the Minnesota Vikings
Niners sign head coach Kyle Shanahan, general manager John Lynch to multi-year extensions
The 49ers announced Friday that they have signed head Kyle Shanahan and general manager John Lynch to multi-year extensions.
Packers' Aaron Jones (hamstring), Christian Watson (hamstring) questionable for Sunday vs. Saints
Packers running back Aaron Jones (hamstring), receiver Christian Watson (hamstring), tackle David Bakhtiari (knee), edge rusher Lukas Van Ness (elbow) and cornerback Jaire Alexander (back) are all questionable.
QB Anthony Richardson (concussion) out, Gardner Minshew to start for Colts vs. Ravens
Indianapolis Colts quarterback Anthony Richardson is not practicing Friday, putting backup Gardner Minshew in line to start Sunday versus the Baltimore Ravens.
NFL news roundup: Latest league updates from Friday, Sept. 22
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Eagles HC Nick Sirianni on balancing workload for RB D'Andre Swift: 'We're going to ride the hot hand'
D'Andre Swift played 58 snaps in Week 2, third-most in his career, and his 31 touches were his second-most in a game. The question for the oft-injured back is whether that sort of workload is sustainable.
Saints rookie RB Kendre Miller expected to make season debut Sunday: 'It just feels good to be back'
New Orleans Saints running back Kendre Miller is expected to make his season debut Sunday against the Green Bay Packers after missing the first two weeks due to a hamstring injury.
Kyle Shanahan: Brock Purdy's career night in 49ers' win over Giants 'definitely wasn't his best game'
Despite facing manic blitzes from Wink Martindale's defense, 49ers QB Brock Purdy finished 25-of-37 passing with a career-high 310 yards and two touchdowns for a 111.3 passer rating.
Daniel Jones on Giants' woeful first-half starts: 'We have to find a way to figure that out'
The New York Giants have been down by double digits in each of the three contests to open the 2023 season. "Yes, it's not what we're trying to do, so we have to find a way to figure that out," quarterback Daniel Jones said following Thursday's 30-12 loss to the Niners.
YAC monster Deebo Samuel not 'awful' in return to form during 49ers' Thursday night win
Having characterized his 2022 season as "awful," 49ers wide receiver Deebo Samuel was just the opposite of that on Thursday night, as he keyed San Francisco's win over New York with a classic performance.