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| Player | Cause | Organization |
|---|---|---|
| Jose Arcega-Whiteside | Cancer | Susan G. Komen |
| Alex Singleton | Youth Health & Fitness | Special Olympics |
| Andre Chachere | DV Awareness | Marjaree Mason Center |
| Anthony Harris | Youth Education | Anthony Harris Foundation / One Love |
| Arryn Siposs | Cancer | Maddie’s Vision |
| Boston Scott | American Neurological Association | American Neurological Association |
| Dallas Goedert | Community Outreach | Pass It On #ForTrevor |
| DeVonta Smith | Autism | Eagles Autism Foundation |
| Gardner Minshew | Health | Movember |
| Jack Driscoll | Substance Abuse | Demand ZERO |
| Jack Stoll | Autism | Eagles Autism Foundation |
| Jake Elliott | Animal Rescue | STAR |
| Jalen Hurts | Women's Sports Foundation | |
| Jalen Reagor | Mental Health | Black Men Heal |
| Jason Kelce | Autism | Eagles Autism Foundation |
| Josiah Scott | ALS | ALS Association |
| Nate Herbig | Autism | Eagles Autism Foundation |
| Patrick Johnson | Autism | Eagles Autism Foundation |
| Rick Lovato | Autism | Eagles Autism Foundation |
| Rodney McLeod | Youth Education | Change Our Future |
| Ross Pierschbacher | Disease Awareness | American Diabetes Association |
| Ryan Kerrigan | Animal Welfare | Road Dogs & Rescue |
| Tyree Jackson | Autism | Eagles Autism Foundation |