Giants QB Eli Manning is the start of the week. Get that and more in this week's edition.

The Steelers are 3-0 with two different starting quarterbacks. Not many other teams could accomplish the same with their star passer suspended.

Tampa Bay Buccaneers backup running back Kareem Huggins will be inactive against the Pittsburgh Steelers today, according to team sources. He will be replaced by Kregg Lumpkin, who spent last season on the Green Bay Packers practice squad. Lumpkin will rotate with starter Cadillac Williams and be actively involved in the game plan.

Injuries are tough to predict, but a number of big-name running backs seem to go down every season. That sort of scenario could open the door for valuable fantasy sleepers like Michael Bush to emerge in 2010.

The running back position has lost some of its luster in fantasy football, but it's still important to have a strong knowledge of all 32 NFL backfields heading into draft day. Michael Fabiano breaks them down.

The 2010 rookie class gave fantasy owners a number of running backs with major potential to consider on draft day. But one runner in particular definitely shines above the rest.