Alex Smith is 9-16 in his career against Super Bowl-winning quarterbacks. This week, he faces Super Bowl XLVIII winner Russell Wilson.

The Falcons lost five straight games before their victory at Tampa Bay in Week 10. The only team with a 5-plus game losing streak in a season in which they made the playoffs was the 1986 Jets.

Four of the Saints' five losses this season have come by three points or less. Their average margin of defeat of 6.0 points is the NFL's second smallest, behind only the Eagles at 4.5.

Odell Beckham Jr. has 100-plus receiving yards in consecutive games. No Giants rookie has ever had three straight 100-yard receiving games.

Peyton Manning has never passed for more than 235 yards in a game against the Rams, which is his lowest career-high against any single opponent. The Rams are the only team against which Manning has not passed for 300-plus yards.

The Cardinals entered the NFL (in Chicago) in 1920; the Lions (as the Spartans of Portsmouth, Ohio) in 1930. These two franchises have posted winning records in the same season only seven times, most recently in 1983.

With a win, Pittsburgh moves to 7-4. The last time Steelers were 7-4 was 2005, when they finished 11-5 and won Super Bowl XL vs. the Seahawks.

The Bills are 5-0 this season when Sammy Watkins has more than 30 receiving yards, but 0-4 when he has 30 or fewer yards.

In his 63rd career start, Mark Sanchez threw for 300-plus yards and 0 INT for the first time in his career. In contrast, Aaron Rodgers has 21 games with 300-plus yards and 0 INT in his career, including three this season.

Tom Brady and Andrew Luck have met two times, once in the 2012 regular season and once in the 2013 Divisional Round. The Patriots outscored Indianapolis in the two games by a combined score of 102-46. Brady's passer rating of 106.9 in those games is almost 50 points better than Luck's 58.2.