The Oakland Raiders lost another quarterback to injury.
NFL Network Insider Ian Rapoport reported after the game that McGloin's injury was to his trapezius muscle, acting like a pinched nerve, per sources. The Raiders aren't ruling out McGloin, but are not optimistic about him playing against the Texans, Rapoport added.
McGloin made the start after Derek Carr suffered a fractured fibula last week.
Fourth-round rookie Connor Cook took over the reins with 1:44 remaining in the first half for a Raiders team attempting to lock down a first-round bye with a win. Cook's first NFL pass was a completion to Amari Cooper.
McGloin struggled prior to exiting. The fourth-year pro completed just 6 of 11 passes for 21 yards. He took a beating on his final drive, getting his head slammed into the turf on a penalty by Broncos defensive lineman Jared Crick. He later had his hand and arm smashed after releasing a pass.
The Broncos' defense stacked the box against a good Raiders run game, daring McGloin to beat them. The backup quarterback couldn't do it early. Before getting hurt, McGloin missed Cooper by a mile on what should have been a long 60-plus yard touchdown.
Oakland earned just 47 total yards and three first downs (one by penalty) on four drives with McGloin under center.
The Raiders trailed by 17 when Cook took over.