Carlos Hyde's arrow is pointing up for Monday Night Football.
The 49ers running back was seen in uniform during Wednesday's practice after being cleared for football activities by team doctors, per multiple reports.
Hyde is returning from the concussion he suffered in San Francisco's preseason game against the Green Bay Packers on Aug. 26.
The third-year back wore a blue no-contact jersey in Wednesday's session, but his return is a promising development for the team's Week 1 showdown with the Los Angeles Rams.
The Niners figure to run the ball plenty under new coach Chip Kelly, with Hyde leading the way ahead of Mike Davis, Shaun Draughn and DuJuan Harris.
For a team lacking skill-player difference-makers at every level, entering the campaign with Hyde in one piece is critical to staying afloat -- if that's what they plan to do -- in the NFC West.
Other injury news we're tracking Wednesday:
- Colts quarterback Andrew Luck (shoulder), linebacker Sio Moore (hamstring) and defensive tackle Henry Anderson (knee) were among six players limited in practice. Indianapolis' secondary isn't completely healthy going into its opener against the Lions: cornerbacks Vontae Davis and Darius Butler both missed practice with ankle injuries.
- Chargers defensive end Joey Bosa missed practice with tightness Wednesday, putting his Week 1 debut in serious doubt.
- Chiefs running back Jamaal Charles and linebacker Tamba Hali were limited in practice with their lingering knee injuries.
- Bears guard Kyle Long (shoulder) and defensive back Kyle Fuller (knee) were limited in practice.
- Redskins running back Matt Jones (shoulder) practiced without a non-contact jersey Wednesday, while the team is still taking it slow with rookie receiver Josh Doctson.
- Texans defensive end J.J. Watt said he feels "100 percent" after recovering from back surgery. Watt was limited in practice, as was rookie wideout Will Fuller who has a hamstring injury.
- Ravens linebacker Elvis Dumervil (foot) did not practice Wednesday and told reporters that he will not play Sunday after suffering a setback in his recovery. Running back Kenneth Dixon (knee) and cornerback Jerraud Powers (ankle) also did not practice.
- Falcons wide receiver Julio Jones was limited in practice with an ankle injury while rookie safety Keanu Neal sat out with a knee injury.
- Titans coach Mike Mularkey told reporters that wide receiver Kendall Wright will not play Sunday against the Vikings as he nurses a hamstring injury. There is no timetable for his return.
- Seahawks rookie guard Germain Ifedi left practice with an ankle injury and was added to the injury report as a limited participant. Tight end Jimmy Graham (knee) was listed as a full participant. In other offensive news, Pete Carroll told reporters the only limitations for running back Thomas Rawls (ankle) are the number of plays.
- Jaguars defensive end Jared Odrick (jaw) and running back Chris Ivory (calf) were limited in practice Wednesday, while defensive tackle Roy Miller (quad) was a full participant.
- Dolphins center Mike Pouncey (hip) and wide receiver DeVante Parker (hamstring) both sat out practice ahead of Miami's season opener in Seattle.
- Lions tight end Eric Ebron (ankle) was full-go in Wednesday's practice, while his receiving mate Golden Tate was limited with an ankle injury.
- Panthers defensive tackle Vernon Butler (hand) is listed as questionable for Carolina's game against Denver but was a full participant in practice on Tuesday and Wednesday.
- Seven Patriots players were limited participants in practice including tight end Rob Gronkowski (hamstring), tackle Nate Solder (hamstring), guard Jonathan Cooper (foot), offensive lineman Shaq Mason (hand) and wide receiver Malcolm Mitchell (elbow).
- Cardinals defensive tackle Frostee Rucker (neck) and cornerback Justin Bethel (foot) were limited in practice. Most notably not listed on Wednesday's injury report? Tyrann Mathieu, who has been rehabbing his season-ending knee injury.
- Jets linebacker David Harris (shoulder), wide receiver Brandon Marshall (hip) and defensive end Leonard Williams (hip) were all limited in practice. Rookie outside linebacker Jordan Jenkins (calf) did not practice Wednesday; he's listed as a first-teamer on the Jets' unofficial depth chart.
