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Brandon Marshall, Alshon Jeffery uncertain to play

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Even in the best circumstances, the Chicago Bears faced a tall order on Sunday night in San Francisco when the 49ers unveil Levi's Stadium. These are not the best circumstances.

Brandon Marshall missed the majority of his third straight practice Friday because of his ankle injury, while his running mate Alshon Jeffery (hamstring) was limited in his return to practice. Both players are listed as questionable on the injury report, but coach Marc Trestman didn't exactly sound a note of optimism on Marshall.

"He just walked-through. At best, it was a light jog," Trestman said.

Jeffery said that he felt good, but noted that practice and playing in a game are different. Trestman indicated that they would have to make some adjustments to the roster, which is not a surprise because another wide receiver (Josh Morgan) is doubtful to play. In short: Santonio Holmes is the only Bears receiver that the team knows will play. And the Bears are missing two starting offensive linemen (Matt Slauson and Roberto Garza.)

Add it all up, and I'm deeply regretting picking the Bears to pull off the upset on Sunday.

UPDATE: The Bears have promoted wide receivers Josh Bellamy and Chris Williams and center Taylor Boggs from the practice squad to the 53-man roster, per the Chicago Tribune.

The latest "Around The NFL Podcast" recaps the Steelers-Ravens game and previews the other 15 games in Week 2.

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