Wayne suffered a non-contact injury to his right knee during the fourth quarter of Indy's 39-33 win over Denver. The Colts' worst fears were realized, and coach Chuck Pagano said the loss "stings" when he confirmed the news Monday.
Stripping Wayne from the passing attack leaves the Colts without their most reliable target. He leads the team in receptions (38) and yards (503) and has been an anchor for young quarterback Andrew Luck. T.Y. Hilton is an ascendant talent, and Darrius Heyward-Bey played a larger role against Denver, but the other wideouts on the roster are just LaVon Brazill and David Reed.
Good teams find a way to overcome injuries and, if we learned anything Sunday night, it's that Indy is a good -- if not a great -- force in the AFC South.