Brown -- wearing a walking boot -- downplayed the injury after the Giants' 28-20 loss.
"It's not that bad of a break," he said, according to the New York Daily News. "Just a tiny crack. ... Not that serious. ... No surgery."
Brown was injured when a helmet hit his leg. He fractured the same leg in November, ending his 2012 season after 10 games.
It's a substantial loss for the Giants, who were counting on a big contribution from Brown as a third-down and goal-line back. It also sets the stage for an even bigger role for David Wilson, who capped an excellent preseason with 36 yards on seven carries against the Patriots. Wilson averaged nearly 7.5 yards per rush over four preseason games.
Ryan Torain and Da'Rel Scott are two in-house options who could step into a bigger role. Torain's ability as a pass protector might give him the edge. The Giants also could look at outside help, with the likes of Cedric Benson and Willis McGahee available.The "Around The League Podcast" is now available on iTunes! Click here to listen and subscribe.