On Friday, Holmes was asked if he'd even be ready for the season.
"I can't answer that question right now," Holmes said, via Manish Mehta of the New York Daily News. "I have to do what the foot says."
Yikes. Holmes is the most valuable player on the Jets' offense. He's in a contract year and won't be eager to risk further injury. These quotes are not encouraging.
"Well, uh ... obviously, there's always concern," Ryan said. "I feel confident that he will be on the field. I don't know when that is, but I feel confident he'll be out there."
The Jets have enough questions at quarterback and running back. Losing Holmes for a big chunk of the regular season would be devastating because the 2010 version of Braylon Edwards is not walking through that door.
Follow Gregg Rosenthal on Twitter @greggrosenthal.