NFL.com and NFL Network reporter Ian Rapoport has his thoughts on the game:
Why this game is intriguing: What the 49ers hope is that this game is badly over-valued. That I've totally blown it. Because if this is a competitive, intense game, that likely means San Francisco will go limping into the playoffs. If the Niners have a tough time with the Cardinals, it might mean the cracks in their foundation are real. At home, in their final regular-season tune-up, with Arizona reeling, the 49ers should roll. Quarterback Colin Kaepernick should thrive, and the Niners D should bounce back, whether or not Justin Smith plays. Oh, and if they want the NFC West crown and a crack at a first-round bye, a nice, easy victory is preferred.
On Twitter: #ARIvsSF