Sanchez, who has 12 touchdown passes against 13 interceptions this season, was benched in favor of 2011 seventh-round draft pick Greg McElroy during the second half of last Sunday's 7-6 win over the Arizona Cardinals.
"At the end of the day, it's my decision and I'm comfortable with the decision," Ryan told reporters during his Wednesday news conference. "I'm actually really looking forward to watching Mark play. ...
"It's one where, obviously, I have to get this decision right, and I believe I have."
Sanchez's struggles this season have epitomized the Jets' tumultuous campaign, underscored by a Thanksgiving night fumble after he ran into his own offensive lineman's rear end and culminating with his benching last weekend.
"I understand that he has to play better, he has to protect the ball better," Ryan said.
NFL.com's Albert Breer reports, via a Jets source, that the decision on who will back up Sanchez likely will hinge on the health of Tim Tebow's ribs. Tebow was inactive for last Sunday's game against the Cardinals.
Ryan told reporters Wednesday that Tebow will be the No. 2 quarterback "if he was completely healthy."
Follow Kevin Patra on Twitter @kpatra