NFL Network's Stacey Dales reported Fred Jackson will start after missing the last two games with a sprained knee suffered in the season opener. He will wear a brace on the joint. The bigger surprise is an active C.J. Spiller seven days after he injured his shoulder. He was expected to miss at least one game.
The question is: How will coach Chan Gailey distribute the carries?
Jackson was the clear-cut No. 1 after he averaged a career-high 5.5 yards per carry before injury ended his 2011 after 10 games. Jackson was on pace for 1,494 yards.
Spiller, however, has muddied the waters in Jackson's absence. His 308 rushing yards are the fourth-most in the NFL and his four touchdowns (3 rushing, 1 receiving) are tied for a league-high.
Spiller has been the league's most improved player three games into 2012.
UPDATE: Jackson started the game and gained 11 yards on the first play from scrimmage for the Bills.