Owens' return originally was listed as questionable, but the Falcons later tweeted that Owens would not return.
Another cornerback, Asante Samuel, sustained a neck injury in the opening period. But, after a quick trip to the locker room for X-rays, he was able to return.
Atlanta was already short-handed at cornerback after Brent Grimes went down with a season-ending injury in the opener.
The Associated Press contributed to this report.