The team will try to trade Samuel before the NFL Draft begins on April 26, according to a Sunday report in the Philadelphia Inquirer.
Samuel, 31, is set to make $8.4 million in base salary next season with a salary cap hit of $9.5 million as part of the contract he signed with the Eagles in 2008.
The Eagles' desire to trade Samuel is nothing new. General manager Howie Roseman said in February that the team will listen to teams interested in a Samuel deal, and the team admitted it tried to deal the cornerback last offseason.
Samuel was upset when the team acquired two high-profile cornerbacks last offseason, signing free-agent Nnamdi Asomugha and trading for Dominique Rodgers-Cromartie.
If he is traded, it won't be a surprise to the four-time Pro Bowl selection. Samuel asked his Twitter followers last month where they'd like to see him end up.